Clustering of Tir during enteropathogenic E. coli infection triggers calcium influx–dependent pyroptosis in intestinal epithelial cells

Clustering of the enteropathogenic Escherichia coli (EPEC) type III secretion system (T3SS) effector translocated intimin receptor (Tir) by intimin leads to actin polymerisation and pyroptotic cell death in macrophages. The effect of Tir clustering on the viability of EPEC-infected intestinal epithe...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Qiyun, Roumeliotis, Theodoros I., Kozik, Zuza, Cepeda-Molero, Massiel, Fernández, Luis Ángel, Shenoy, Avinash R., Bakal, Chris, Frankel, Gad, Choudhary, Jyoti S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773185/
https://www.ncbi.nlm.nih.gov/pubmed/33378358
http://dx.doi.org/10.1371/journal.pbio.3000986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773185/
https://www.ncbi.nlm.nih.gov/pubmed/33378358
http://dx.doi.org/10.1371/journal.pbio.3000986

Ejemplares similares