Cargando…

Clustering of Tir during enteropathogenic E. coli infection triggers calcium influx–dependent pyroptosis in intestinal epithelial cells

Clustering of the enteropathogenic Escherichia coli (EPEC) type III secretion system (T3SS) effector translocated intimin receptor (Tir) by intimin leads to actin polymerisation and pyroptotic cell death in macrophages. The effect of Tir clustering on the viability of EPEC-infected intestinal epithe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhong, Qiyun, Roumeliotis, Theodoros I., Kozik, Zuza, Cepeda-Molero, Massiel, Fernández, Luis Ángel, Shenoy, Avinash R., Bakal, Chris, Frankel, Gad, Choudhary, Jyoti S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773185/ https://www.ncbi.nlm.nih.gov/pubmed/33378358 http://dx.doi.org/10.1371/journal.pbio.3000986

Ejemplares similares

Attaching and effacing (A/E) lesion formation by enteropathogenic E. coli on human intestinal mucosa is dependent on non-LEE effectors
por: Cepeda-Molero, Massiel, et al.
Publicado: (2017)

Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo
por: Crepin, Valérie F, et al.
Publicado: (2010)

Tir Is Essential for the Recruitment of Tks5 to Enteropathogenic Escherichia coli Pedestals
por: Jensen, Helene H., et al.
Publicado: (2015)

Intestinal Epithelial Cells and the Microbiome Undergo Swift Reprogramming at the Inception of Colonic Citrobacter rodentium Infection
por: Hopkins, Eve G. D., et al.
Publicado: (2019)

Enteropathogenic Escherichia coli Stimulates Effector-Driven Rapid Caspase-4 Activation in Human Macrophages
por: Goddard, Philippa J., et al.
Publicado: (2019)

The mechanisms used by enteropathogenic Escherichia coli to control filopodia dynamics
por: Berger, Cedric N, et al.
Publicado: (2009)

Proteomic characterisation of triple negative breast cancer cells following CDK4/6 inhibition
por: Beykou, Melina, et al.
Publicado: (2022)

Study of polymorphisms in tir, eae and tccP2 genes in enterohaemorrhagic and enteropathogenic Escherichia coli of serogroup O26
por: Bardiau, Marjorie, et al.
Publicado: (2011)

Crk Adaptors Negatively Regulate Actin Polymerization in Pedestals Formed by Enteropathogenic Escherichia coli (EPEC) by Binding to Tir Effector
por: Nieto-Pelegrin, Elvira, et al.
Publicado: (2014)

EspJ of enteropathogenic and enterohaemorrhagic Escherichia coli inhibits opsono-phagocytosis
por: Marchès, Oliver, et al.
Publicado: (2008)

Tir
Publicado: (1965)

AUX1-mediated root hair auxin influx governs SCF(TIR1/AFB)-type Ca(2+) signaling
por: Dindas, Julian, et al.
Publicado: (2018)

The Enteropathogenic E. coli (EPEC) Tir Effector Inhibits NF-κB Activity by Targeting TNFα Receptor-Associated Factors
por: Ruchaud-Sparagano, Marie-Hélène, et al.
Publicado: (2011)

Characterization of proteome-size scaling by integrative omics reveals mechanisms of proliferation control in cancer
por: Jones, Ian, et al.
Publicado: (2023)

Citrobacter rodentium Infection Induces Persistent Molecular Changes and Interferon Gamma-Dependent Major Histocompatibility Complex Class II Expression in the Colonic Epithelium
por: Mullineaux-Sanders, Caroline, et al.
Publicado: (2022)

Tir & lir /
por: Redonnet, Marie
Publicado: (1988)

Evaluation of a Dual Isolation Width Acquisition Method for Isobaric Labeling Ratio Decompression
por: Roumeliotis, Theodoros I., et al.
Publicado: (2018)

The enteropathogenic Escherichia coli effector NleH inhibits apoptosis induced by Clostridium difficile toxin B
por: Robinson, Keith S., et al.
Publicado: (2010)

Citrobacter rodentium induces rapid and unique metabolic and inflammatory responses in mice suffering from severe disease
por: Carson, Danielle, et al.
Publicado: (2019)

EspZ of Enteropathogenic and Enterohemorrhagic Escherichia coli Regulates Type III Secretion System Protein Translocation
por: Berger, Cedric N., et al.
Publicado: (2012)

A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation
por: Pearson, Jaclyn S, et al.
Publicado: (2011)

Identifying and characterising Thrap3, Bclaf1 and Erh interactions using cross-linking mass spectrometry
por: Shcherbakova, Liudmila, et al.
Publicado: (2023)

Mouse models for bacterial enteropathogen infections: insights into the role of colonization resistance
por: Herzog, Mathias K.-M., et al.
Publicado: (2023)

Distribution of espM and espT among enteropathogenic and enterohaemorrhagic Escherichia coli
por: Arbeloa, Ana, et al.
Publicado: (2009)

The type III secretion system effector EspO of enterohaemorrhagic Escherichia coli inhibits apoptosis through an interaction with HAX-1
por: Chatterjee, Sharanya, et al.
Publicado: (2021)

Correction to: The Role of TIR-NBS and TIR-X Proteins in Plant Basal Defense Responses
Publicado: (2022)

The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses
por: Berger, Cedric N., et al.
Publicado: (2018)

The T3SS Effector EspT Defines a New Category of Invasive Enteropathogenic E. coli (EPEC) Which Form Intracellular Actin Pedestals
por: Bulgin, Richard, et al.
Publicado: (2009)

Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly
por: Campellone, Kenneth G., et al.
Publicado: (2004)

Differential requirement of TIR enzymatic activities in TIR-type immune receptor SNC1-mediated immunity
por: Tian, Lei, et al.
Publicado: (2022)

Structural Evolution of TIR-Domain Signalosomes
por: Nimma, Surekha, et al.
Publicado: (2021)

Vying for the control of inflammasomes: The cytosolic frontier of enteric bacterial pathogen–host interactions
por: Sanchez‐Garrido, Julia, et al.
Publicado: (2020)

High resolution mapping of trypanosomosis resistance loci Tir2 and Tir3 using F12 advanced intercross lines with major locus Tir1 fixed for the susceptible allele
por: Nganga, Joseph K, et al.
Publicado: (2010)

Lactoferrin-based food supplements trigger toxin production of enteropathogenic Bacillus cereus
por: Jugert, Clara-Sophie, et al.
Publicado: (2023)

Supersymétrie : Le LEP règle le tir
Publicado: (1991)

Combining TIR and FRET in Molecular Test Systems
por: Schneckenburger, Herbert, et al.
Publicado: (2019)

Broader functions of TIR domains in Arabidopsis immunity
por: Jacob, Pierre, et al.
Publicado: (2023)

Transcriptome-Wide Identification of Coding and Noncoding RNA-Binding Proteins Defines the Comprehensive RNA Interactome of Leishmania mexicana
por: Kalesh, Karunakaran, et al.
Publicado: (2022)

Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling
por: Koliopoulos, Marios G., et al.
Publicado: (2022)

Author Correction: Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling
por: Koliopoulos, Marios G., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_te04g333t18n71q2s29ql6qaij