Triphenylphosphonium derivatives disrupt metabolism and inhibit melanoma growth in vivo when delivered via a thermosensitive hydrogel

Despite dramatic improvements in outcomes arising from the introduction of targeted therapies and immunotherapies, metastatic melanoma is a highly resistant form of cancer with 5 year survival rates of <35%. Drug resistance is frequently reported to be associated with changes in oxidative metabol...

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Detalles Bibliográficos
Autores principales: Kloepping, Kyle C., Kraus, Alora S., Hedlund, Devin K., Gnade, Colette M., Wagner, Brett A., McCormick, Michael L., Fath, Melissa A., Seol, Dongrim, Lim, Tae-Hong, Buettner, Garry R., Goswami, Prabhat C., Pigge, F. Christopher, Spitz, Douglas R., Schultz, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773266/
https://www.ncbi.nlm.nih.gov/pubmed/33378390
http://dx.doi.org/10.1371/journal.pone.0244540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773266/
https://www.ncbi.nlm.nih.gov/pubmed/33378390
http://dx.doi.org/10.1371/journal.pone.0244540

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