Challenges and Perspectives for Therapeutic Targeting of Myeloproliferative Neoplasms

Myeloproliferative neoplasms (MPNs) are hematopoietic stem cell disorders with dysregulated myeloid blood cell production and propensity for transformation to acute myeloid leukemia, thrombosis, and bleeding. Acquired mutations in JAK2, MPL, and CALR converge on hyperactivation of Janus kinase 2 (JA...

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Detalles Bibliográficos
Autores principales: Brkic, Sime, Meyer, Sara C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773330/
https://www.ncbi.nlm.nih.gov/pubmed/33403355
http://dx.doi.org/10.1097/HS9.0000000000000516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773330/
https://www.ncbi.nlm.nih.gov/pubmed/33403355
http://dx.doi.org/10.1097/HS9.0000000000000516

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