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AT1R/GSK-3β/mTOR Signaling Pathway Involved in Angiotensin II-Induced Neuronal Apoptosis after HIE Both In Vitro and In Vivo

OBJECTIVE: The focus of the present study is to evaluate the effects of Angiotensin II (Ang II) on neuronal apoptosis after HIE and the potential underlying mechanisms. METHODS: Primary neonatal rat cortical neurons were used to study the oxygen-glucose deprivation (OGD) cell model. The expressions...

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Detalles Bibliográficos
Autores principales: Si, Wei, Li, Banghui, Lenahan, Cameron, Li, Shirong, Gu, Ran, Qu, Hao, Wang, Lu, Liu, Jiapeng, Tian, Tian, Wang, Qian, XikeWang, Hu, Xiao, Zuo, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773460/
https://www.ncbi.nlm.nih.gov/pubmed/33425219
http://dx.doi.org/10.1155/2020/8864323