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Joint epitope selection and spacer design for string-of-beads vaccines

MOTIVATION: Conceptually, epitope-based vaccine design poses two distinct problems: (i) selecting the best epitopes to elicit the strongest possible immune response and (ii) arranging and linking them through short spacer sequences to string-of-beads vaccines, so that their recovery likelihood durin...

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Detalles Bibliográficos
Autores principales: Dorigatti, Emilio, Schubert, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773482/
https://www.ncbi.nlm.nih.gov/pubmed/33381831
http://dx.doi.org/10.1093/bioinformatics/btaa790