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Finding orthologous gene blocks in bacteria: the computational hardness of the problem and novel methods to address it

MOTIVATION: The evolution of complexity is one of the most fascinating and challenging problems in modern biology, and tracing the evolution of complex traits is an open problem. In bacteria, operons and gene blocks provide a model of tractable evolutionary complexity at the genomic level. Gene bloc...

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Detalles Bibliográficos
Autores principales: Nguyen, Huy N, Markin, Alexey, Friedberg, Iddo, Eulenstein, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773486/
https://www.ncbi.nlm.nih.gov/pubmed/33381825
http://dx.doi.org/10.1093/bioinformatics/btaa794