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Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts

Canonical mRNA translation in eukaryotes begins with the formation of the 43S pre-initiation complex (PIC). Its assembly requires binding of initiator Met-tRNA(i)(Met) and several eukaryotic initiation factors (eIFs) to the small ribosomal subunit (40S). Compared to their mammalian hosts, trypanosom...

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Detalles Bibliográficos
Autores principales:	Bochler, Anthony, Querido, Jailson Brito, Prilepskaja, Terezie, Soufari, Heddy, Simonetti, Angelita, Del Cistia, Mayara Lucia, Kuhn, Lauriane, Ribeiro, Aline Rimoldi, Valášek, Leoš Shivaya, Hashem, Yaser
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773551/ https://www.ncbi.nlm.nih.gov/pubmed/33357443 http://dx.doi.org/10.1016/j.celrep.2020.108534

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