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Dysfunctional Autophagy and Endolysosomal System in Neurodegenerative Diseases: Relevance and Therapeutic Options

Autophagy and endolysosomal trafficking are crucial in neuronal development, function and survival. These processes ensure efficient removal of misfolded aggregation-prone proteins and damaged organelles, such as dysfunctional mitochondria, thus allowing the maintenance of proper cellular homeostasi...

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Detalles Bibliográficos
Autores principales: Giovedì, Silvia, Ravanelli, Margherita Maria, Parisi, Barbara, Bettegazzi, Barbara, Guarnieri, Fabrizia Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773602/
https://www.ncbi.nlm.nih.gov/pubmed/33390907
http://dx.doi.org/10.3389/fncel.2020.602116