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Life Cycle of the Cardiac Voltage-Gated Sodium Channel Na(V)1.5

Cardiac voltage-gated sodium channel Na(V)1.5, encoded by SCN5A, is crucial for the upstroke of action potential and excitation of cardiomyocytes. Na(V)1.5 undergoes complex processes before it reaches the target membrane microdomains and performs normal functions. A variety of protein partners are...

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Detalles Bibliográficos
Autores principales: Dong, Caijuan, Wang, Ya, Ma, Aiqun, Wang, Tingzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773603/
https://www.ncbi.nlm.nih.gov/pubmed/33391024
http://dx.doi.org/10.3389/fphys.2020.609733