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Identification of Compounds With Glucocorticoid Sparing Effects on Suppression of Chemokine and Cytokine Production by Rheumatoid Arthritis Fibroblast-Like Synoviocytes

In recent years target based drug discovery has expanded our therapeutic armamentarium in the treatment of inflammatory and autoimmune diseases. Despite these advances and adverse effects, glucocorticoids remain reliable agents that are used in many of these diseases. The anti-inflammatory mechanism...

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Detalles Bibliográficos
Autores principales: Hosoya, Tadashi, Shukla, Nikunj M., Fujita, Yuya, Yao, Shiyin, Lao, Fitzgerald S., Baba, Hiroyuki, Yasuda, Shinsuke, Cottam, Howard B., Carson, Dennis A., Hayashi, Tomoko, Corr, Maripat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773657/
https://www.ncbi.nlm.nih.gov/pubmed/33390996
http://dx.doi.org/10.3389/fphar.2020.607713