Modulation of the Acetylcholine Receptor Clustering Pathway Improves Neuromuscular Junction Structure and Muscle Strength in a Mouse Model of Congenital Myasthenic Syndrome

Introduction: Congenital myasthenic syndromes (CMS) are a diverse group of inherited neuromuscular disorders characterized by a failure of synaptic transmission at the neuromuscular junction (NMJ). CMS often present early with fatigable weakness and can be fatal through respiratory complications. Th...

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Detalles Bibliográficos
Autores principales: Spendiff, Sally, Howarth, Rachel, McMacken, Grace, Davey, Tracey, Quinlan, Kaitlyn, O'Connor, Emily, Slater, Clarke, Hettwer, Stefan, Mäder, Armin, Roos, Andreas, Horvath, Rita, Lochmüller, Hanns
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773664/
https://www.ncbi.nlm.nih.gov/pubmed/33390901
http://dx.doi.org/10.3389/fnmol.2020.594220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773664/
https://www.ncbi.nlm.nih.gov/pubmed/33390901
http://dx.doi.org/10.3389/fnmol.2020.594220

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