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ZG16 regulates PD-L1 expression and promotes local immunity in colon cancer

CRC is a heterogeneous disease due to global molecular alterations, including mismatch-repair-deficient (dMMR) and microsatellite instability-high (MSI-H). Immunotherapy has achieved durable responses in a subset of patients with dMMR-MSI-H metastatic CRC. It has been showed that Loss of ZG16 is hig...

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Detalles Bibliográficos
Autores principales: Meng, Hui, Ding, Yi, Liu, Enjie, Li, Wencai, Wang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773682/
https://www.ncbi.nlm.nih.gov/pubmed/33360840
http://dx.doi.org/10.1016/j.tranon.2020.101003