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Mycobacterium tuberculosis Cells Surviving in the Continued Presence of Bactericidal Concentrations of Rifampicin in vitro Develop Negatively Charged Thickened Capsular Outer Layer That Restricts Permeability to the Antibiotic

Majority of the cells in the bacterial populations exposed to lethal concentrations of antibiotics for prolonged duration succumbs to the antibiotics’ sterilizing activity. The remaining cells survive by diverse mechanisms that include reduced permeability of the antibiotics. However, in the cells s...

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Detalles Bibliográficos
Autores principales: Sebastian, Jees, Nair, Rashmi Ravindran, Swaminath, Sharmada, Ajitkumar, Parthasarathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773709/
https://www.ncbi.nlm.nih.gov/pubmed/33391194
http://dx.doi.org/10.3389/fmicb.2020.554795