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Equilibrative Nucleoside Transporters-1 Inhibitors Act as Anti-epileptic Agents by Inhibiting Glutamatergic Transmission

Background and Purpose: Adenosine dysregulation is associated with the occurrence of the epilepsy and equilibrative nucleoside transporters-1 (ENT-1) functions as an important regulator of extracellular adenosine in the brain. This study was aimed to prove the anti-epileptic effect of BBB permeable...

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Detalles Bibliográficos
Autores principales: Ho, Shih-Yin, Chen, I-Chun, Chang, Kai-Chieh, Lin, Hsiao-Ru, Tsai, Che-Wen, Lin, Chun-Jung, Liou, Horng-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773772/
https://www.ncbi.nlm.nih.gov/pubmed/33390891
http://dx.doi.org/10.3389/fnins.2020.610898