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DJ-1 Regulates Microglial Polarization Through P62-Mediated TRAF6/IRF5 Signaling in Cerebral Ischemia-Reperfusion

The polarization of microglia/macrophage, the resident immune cells in the brain, plays an important role in the injury and repair associated with ischemia-reperfusion (I/R). Previous studies have shown that DJ-1 has a protective effect in cerebral I/R. We found that DJ-1 regulates the polarization...

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Detalles Bibliográficos
Autores principales: Wang, Tingting, Zhao, Na, Peng, Li, Li, Yumei, Huang, Xiaohuan, Zhu, Jin, Chen, Yanlin, Yu, Shanshan, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773790/
https://www.ncbi.nlm.nih.gov/pubmed/33392187
http://dx.doi.org/10.3389/fcell.2020.593890