Cargando…

DJ-1 Regulates Microglial Polarization Through P62-Mediated TRAF6/IRF5 Signaling in Cerebral Ischemia-Reperfusion

The polarization of microglia/macrophage, the resident immune cells in the brain, plays an important role in the injury and repair associated with ischemia-reperfusion (I/R). Previous studies have shown that DJ-1 has a protective effect in cerebral I/R. We found that DJ-1 regulates the polarization...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Tingting, Zhao, Na, Peng, Li, Li, Yumei, Huang, Xiaohuan, Zhu, Jin, Chen, Yanlin, Yu, Shanshan, Zhao, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773790/ https://www.ncbi.nlm.nih.gov/pubmed/33392187 http://dx.doi.org/10.3389/fcell.2020.593890

Ejemplares similares

Roles of TRAFs in Ischemia-Reperfusion Injury
por: Zhou, Wei, et al.
Publicado: (2020)

Propofol Mediated Protection of the Brain From Ischemia/Reperfusion Injury Through the Regulation of Microglial Connexin 43
por: Zhang, Tingting, et al.
Publicado: (2021)

Sestrin2 Regulates Osteoclastogenesis via the p62-TRAF6 Interaction
por: Oh, Sue Young, et al.
Publicado: (2021)

Effect of DJ-1 on the neuroprotection of astrocytes subjected to cerebral ischemia/reperfusion injury
por: Peng, Li, et al.
Publicado: (2018)

DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke
por: Peng, Li, et al.
Publicado: (2020)

The Role of the Signaling Pathways Involved in the Protective Effect of Exogenous Hydrogen Sulfide on Myocardial Ischemia-Reperfusion Injury
por: Lv, Shuangyu, et al.
Publicado: (2021)

Perspectives on mitochondrial relevance in cardiac ischemia/reperfusion injury
por: Pedriali, Gaia, et al.
Publicado: (2022)

Mechanism of N-acetylcysteine in alleviating diabetic myocardial ischemia reperfusion injury by regulating PTEN/Akt pathway through promoting DJ-1
por: Li, Wenyuan, et al.
Publicado: (2020)

TREM2, Driving the Microglial Polarization, Has a TLR4 Sensitivity Profile After Subarachnoid Hemorrhage
por: Hu, Yangchun, et al.
Publicado: (2021)

Prolylcarboxypeptidase Mitigates Myocardial Ischemia/Reperfusion Injury by Stabilizing Mitophagy
por: Hao, Panpan, et al.
Publicado: (2020)

Ferroptosis: A Novel Therapeutic Target for Ischemia-Reperfusion Injury
por: Chen, Yunqing, et al.
Publicado: (2021)

Responses of hepatic sinusoidal cells to liver ischemia–reperfusion injury
por: Ito, Yoshiya, et al.
Publicado: (2023)

Phosphorylation of Microglial IRF5 and IRF4 by IRAK4 Regulates Inflammatory Responses to Ischemia
por: Ngwa, Conelius, et al.
Publicado: (2021)

Cerebral Ischemia-Reperfusion Is Associated With Upregulation of Cofilin-1 in the Motor Cortex
por: Xu, Ming-Shu, et al.
Publicado: (2021)

Cell Death and Exosomes Regulation After Myocardial Infarction and Ischemia-Reperfusion
por: Wu, Xun, et al.
Publicado: (2021)

Tea Polyphenols Prevent Sepsis-Induced Lung Injury via Promoting Translocation of DJ-1 to Mitochondria
por: Jia, Chun-Mei, et al.
Publicado: (2021)

A Novel Insight Into the Fate of Cardiomyocytes in Ischemia-Reperfusion Injury: From Iron Metabolism to Ferroptosis
por: Li, Jing-yan, et al.
Publicado: (2021)

AMPKα2 Overexpression Reduces Cardiomyocyte Ischemia-Reperfusion Injury Through Normalization of Mitochondrial Dynamics
por: Deng, Yuanyan, et al.
Publicado: (2020)

DJ-1: A promising therapeutic candidate for ischemia-reperfusion injury
por: De Lazzari, Federica, et al.
Publicado: (2021)

Inhibition of PDE1-B by Vinpocetine Regulates Microglial Exosomes and Polarization Through Enhancing Autophagic Flux for Neuroprotection Against Ischemic Stroke
por: Zang, Jiankun, et al.
Publicado: (2021)

Fibroblast Growth Factor 2 Attenuates Renal Ischemia-Reperfusion Injury via Inhibition of Endoplasmic Reticulum Stress
por: Tan, Xiaohua, et al.
Publicado: (2020)

Depletion of Toll-Like Receptor-9 Attenuates Renal Tubulointerstitial Fibrosis After Ischemia-Reperfusion Injury
por: Zheng, Haofeng, et al.
Publicado: (2021)

CTRP1 Attenuates Cerebral Ischemia/Reperfusion Injury via the PERK Signaling Pathway
por: Fei, Huizhi, et al.
Publicado: (2021)

Succinate metabolism: a promising therapeutic target for inflammation, ischemia/reperfusion injury and cancer
por: Zhang, Wenhui, et al.
Publicado: (2023)

MiR-132-3p Modulates MEKK3-Dependent NF-κB and p38/JNK Signaling Pathways to Alleviate Spinal Cord Ischemia-Reperfusion Injury by Hindering M1 Polarization of Macrophages
por: Fang, Hua, et al.
Publicado: (2021)

Fas-Activated Serine/Threonine Kinase Governs Cardiac Mitochondrial Complex I Functional Integrity in Ischemia/Reperfusion Heart
por: Chen, Xiyao, et al.
Publicado: (2021)

ZDHHC11 Positively Regulates NF-κB Activation by Enhancing TRAF6 Oligomerization
por: Liu, Enping, et al.
Publicado: (2021)

Mettl14 Attenuates Cardiac Ischemia/Reperfusion Injury by Regulating Wnt1/β-Catenin Signaling Pathway
por: Pang, Ping, et al.
Publicado: (2021)

The Novel LncRNA AK035396 Drives Cardiomyocyte Apoptosis Through Mterf1 in Myocardial Ischemia/Reperfusion Injury
por: Xu, Zhaoyan, et al.
Publicado: (2021)

The Interaction of TRAF6 With Neuroplastin Promotes Spinogenesis During Early Neuronal Development
por: Vemula, Sampath Kumar, et al.
Publicado: (2020)

TRAF1 is a key mediator for hepatic ischemia/reperfusion injury
por: Zhang, X-F, et al.
Publicado: (2014)

Adipose-Derived Stem Cells Protect Ischemia-Reperfusion and Partial Hepatectomy by Attenuating Endoplasmic Reticulum Stress
por: Jiao, Zhihui, et al.
Publicado: (2020)

Direct modulation of microglial function by electrical field
por: Lennikov, Anton, et al.
Publicado: (2022)

Mfn2 Overexpression Attenuates Cardio-Cerebrovascular Ischemia–Reperfusion Injury Through Mitochondrial Fusion and Activation of the AMPK/Sirt3 Signaling
por: Liu, Min, et al.
Publicado: (2020)

Sp1 Targeted PARP1 Inhibition Protects Cardiomyocytes From Myocardial Ischemia–Reperfusion Injury via Downregulation of Autophagy
por: Xu, Yifeng, et al.
Publicado: (2021)

DJ-1 Deficiency in Hepatocytes Improves Liver Ischemia-Reperfusion Injury by Enhancing Mitophagy
por: Xu, Min, et al.
Publicado: (2021)

Corrigendum: ZDHHC11 Positively Regulates NF-κB Activation by Enhancing TRAF6 Oligomerization
por: Liu, Enping, et al.
Publicado: (2021)

YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB
por: Schimmack, Gisela, et al.
Publicado: (2017)

miR-146a-5p Plays an Oncogenic Role in NSCLC via Suppression of TRAF6
por: Liu, Xiangdong, et al.
Publicado: (2020)

Tanshinone IIA Protects Against Cerebral Ischemia Reperfusion Injury by Regulating Microglial Activation and Polarization via NF-κB Pathway
por: Song, Zhibing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lm5iqsjgjoq5rt784aqu8pf3ak