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MFG-E8-derived peptide attenuates inflammation and injury after renal ischemia-reperfusion in mice

BACKGROUND: Renal ischemia-reperfusion (renal I/R) injury may lead to acute kidney injury (AKI). After renal I/R, proinflammatory mediators cause immune cell infiltration and further injury. Milk fat globule-epidermal growth factor-factor 8 (MFG-E8) is a protein involved in cell-cell and cell-matrix...

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Detalles Bibliográficos
Autores principales: Last, Jordan, Brenner, Max, Yen, Hao-Ting, Aziz, Monowar, Denning, Naomi-Liza, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773867/
https://www.ncbi.nlm.nih.gov/pubmed/33409388
http://dx.doi.org/10.1016/j.heliyon.2020.e05794