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Aberrant alternative splicing of HTR2A exon II in peripheral blood lymphocytes of drug-naïve schizophrenic patients

The aim of the study was to characterize the pattern of transcript isoforms of HTR2A exon II in lymphocytes of the blood as peripheral biomarkers of schizophrenia development and the effectiveness of antipsychotic therapy. We primarily observed an increase in mRNA levels and elevation of alternative...

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Detalles Bibliográficos
Autores principales: Grunina, Maria N., Belinskaia, Mariia A., Zhuravlev, Alexander S., Nasyrova, Regina F., Krupitsky, Evgeny M., Taraskina, Anastasiya E., Zabotina, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773876/
https://www.ncbi.nlm.nih.gov/pubmed/33409390
http://dx.doi.org/10.1016/j.heliyon.2020.e05809