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Mir-124 Attenuates STAT3-Mediated TH17 Differentiation in Colitis-Driven Colon Cancer

BACKGROUND: Inflammation often induces regeneration to repair the tissue damage. However, chronic inflammation can transform temporary hyperplasia into a fertile ground for tumorigenesis. Here, we demonstrate that the miR-124 acts as a safeguard to inhibit the pro-inflammatory production and reparat...

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Detalles Bibliográficos
Autores principales: Lin, Shiyong, Liu, Qianwen, Wen, Jing, Bai, Kunhao, Guo, Yandong, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773897/
https://www.ncbi.nlm.nih.gov/pubmed/33392070
http://dx.doi.org/10.3389/fonc.2020.570128