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Amylin receptor insensitivity impairs hypothalamic POMC neuron differentiation in the male offspring of maternal high-fat diet-fed mice

OBJECTIVE: Amylin was found to regulate glucose and lipid metabolism by acting on the arcuate nucleus of the hypothalamus (ARC). Maternal high-fat diet (HFD) induces sex-specific metabolic diseases mediated by the ARC in offspring. This study was performed to explore 1) the effect of maternal HFD-in...

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Detalles Bibliográficos
Autores principales: Li, Cheng, Xu, Jing-Jing, Hu, Hong-Tao, Shi, Chao-Yi, Yu, Chuan-Jin, Sheng, Jian-Zhong, Wu, Yan-Ting, Huang, He-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773963/
https://www.ncbi.nlm.nih.gov/pubmed/33279727
http://dx.doi.org/10.1016/j.molmet.2020.101135