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Amylin receptor insensitivity impairs hypothalamic POMC neuron differentiation in the male offspring of maternal high-fat diet-fed mice
OBJECTIVE: Amylin was found to regulate glucose and lipid metabolism by acting on the arcuate nucleus of the hypothalamus (ARC). Maternal high-fat diet (HFD) induces sex-specific metabolic diseases mediated by the ARC in offspring. This study was performed to explore 1) the effect of maternal HFD-in...
Autores principales: | Li, Cheng, Xu, Jing-Jing, Hu, Hong-Tao, Shi, Chao-Yi, Yu, Chuan-Jin, Sheng, Jian-Zhong, Wu, Yan-Ting, Huang, He-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773963/ https://www.ncbi.nlm.nih.gov/pubmed/33279727 http://dx.doi.org/10.1016/j.molmet.2020.101135 |
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