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Alteration of the Premature tRNA Landscape by Gammaherpesvirus Infection

Transfer RNAs (tRNAs) are transcribed by RNA polymerase III (RNAPIII) and play a central role in decoding our genome, yet their expression and noncanonical function remain understudied. Many DNA tumor viruses enhance the activity of RNAPIII, yet whether infection alters tRNA expression is largely un...

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Detalles Bibliográficos
Autores principales: Tucker, Jessica M., Schaller, Aaron M., Willis, Ian, Glaunsinger, Britt A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773990/
https://www.ncbi.nlm.nih.gov/pubmed/33323507
http://dx.doi.org/10.1128/mBio.02664-20