The Bactericidal Fatty Acid Mimetic 2CCA-1 Selectively Targets Pneumococcal Extracellular Polyunsaturated Fatty Acid Metabolism

Streptococcus pneumoniae, a major cause of pneumonia, sepsis, and meningitis worldwide, has the nasopharynges of small children as its main ecological niche. Depletion of pneumococci from this niche would reduce the disease burden and could be achieved using small molecules with narrow-spectrum anti...

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Detalles Bibliográficos
Autores principales: Reithuber, Elisabeth, Nannapaneni, Priyanka, Rzhepishevska, Olena, Lindgren, Anders E. G., Ilchenko, Oleksandr, Normark, Staffan, Almqvist, Fredrik, Henriques-Normark, Birgitta, Mellroth, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773995/
https://www.ncbi.nlm.nih.gov/pubmed/33323510
http://dx.doi.org/10.1128/mBio.03027-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773995/
https://www.ncbi.nlm.nih.gov/pubmed/33323510
http://dx.doi.org/10.1128/mBio.03027-20

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