Cargando…

A Noncanonical DNA Damage Checkpoint Response in a Major Fungal Pathogen

DNA damage checkpoints are key guardians of genome integrity. Eukaryotic cells respond to DNA damage by triggering extensive phosphorylation of Rad53/CHK2 effector kinase, whereupon activated Rad53/CHK2 mediates further aspects of checkpoint activation, including cell cycle arrest and transcriptiona...

Descripción completa

Detalles Bibliográficos
Autores principales: Shor, Erika, Garcia-Rubio, Rocio, DeGregorio, Lucius, Perlin, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773997/
https://www.ncbi.nlm.nih.gov/pubmed/33323516
http://dx.doi.org/10.1128/mBio.03044-20