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A Noncanonical DNA Damage Checkpoint Response in a Major Fungal Pathogen
DNA damage checkpoints are key guardians of genome integrity. Eukaryotic cells respond to DNA damage by triggering extensive phosphorylation of Rad53/CHK2 effector kinase, whereupon activated Rad53/CHK2 mediates further aspects of checkpoint activation, including cell cycle arrest and transcriptiona...
Autores principales: | Shor, Erika, Garcia-Rubio, Rocio, DeGregorio, Lucius, Perlin, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773997/ https://www.ncbi.nlm.nih.gov/pubmed/33323516 http://dx.doi.org/10.1128/mBio.03044-20 |
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