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Involvement of Müller Glial Autoinduction of TGF-β in Diabetic Fibrovascular Proliferation Via Glial–Mesenchymal Transition

PURPOSE: Müller glial–mesenchymal transition (GMT) is reported as the fibrogenic mechanism promoted by TGF-β–SNAIL axis in Müller cells transdifferentiated into myofibroblasts. Here we show the multifaceted involvement of TGF-β in diabetic fibrovascular proliferation via Müller GMT and VEGF-A produc...

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Detalles Bibliográficos
Autores principales: Wu, Di, Kanda, Atsuhiro, Liu, Ye, Noda, Kousuke, Murata, Miyuki, Ishida, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774059/
https://www.ncbi.nlm.nih.gov/pubmed/33369638
http://dx.doi.org/10.1167/iovs.61.14.29