Cargando…

Involvement of Müller Glial Autoinduction of TGF-β in Diabetic Fibrovascular Proliferation Via Glial–Mesenchymal Transition

PURPOSE: Müller glial–mesenchymal transition (GMT) is reported as the fibrogenic mechanism promoted by TGF-β–SNAIL axis in Müller cells transdifferentiated into myofibroblasts. Here we show the multifaceted involvement of TGF-β in diabetic fibrovascular proliferation via Müller GMT and VEGF-A produc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Di, Kanda, Atsuhiro, Liu, Ye, Noda, Kousuke, Murata, Miyuki, Ishida, Susumu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2020
Materias:	Retinal Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774059/ https://www.ncbi.nlm.nih.gov/pubmed/33369638 http://dx.doi.org/10.1167/iovs.61.14.29

Ejemplares similares

Regulation of Spermine Oxidase through Hypoxia-Inducible Factor-1α Signaling in Retinal Glial Cells under Hypoxic Conditions
por: Wu, Di, et al.
Publicado: (2020)

TGF-β-SNAIL axis induces Müller glial-mesenchymal transition in the pathogenesis of idiopathic epiretinal membrane
por: Kanda, Atsuhiro, et al.
Publicado: (2019)

Hypoxia Induces Galectin-1 Expression Via Autoinduction of Placental Growth Factor in Retinal Pigment Epithelium Cells
por: Yamamoto, Taku, et al.
Publicado: (2021)

Glucocorticoid‐transactivated TSC22D3 attenuates hypoxia‐ and diabetes‐induced Müller glial galectin‐1 expression via HIF‐1α destabilization
por: Kanda, Atsuhiro, et al.
Publicado: (2020)

Phosphorylation of αB-Crystallin Involves Interleukin-1β-Mediated Intracellular Retention in Retinal Müller Cells: A New Mechanism Underlying Fibrovascular Membrane Formation
por: Yamamoto, Taku, et al.
Publicado: (2023)

Rapid, Dynamic Activation of Müller Glial Stem Cell Responses in Zebrafish
por: Sifuentes, Christopher J., et al.
Publicado: (2016)

Glucocorticoid receptor inhibits Müller glial galectin‐1 expression via DUSP1‐dependent and ‐independent deactivation of AP‐1 signalling
por: Hirose, Ikuyo, et al.
Publicado: (2019)

Diabetic Müller-Glial-Cell-Specific Il6ra Knockout Mice Exhibit Accelerated Retinal Functional Decline and Thinning of the Inner Nuclear Layer
por: Glass, Joshua, et al.
Publicado: (2023)

Subretinal Glial Membranes in Eyes With Geographic Atrophy
por: Edwards, Malia M., et al.
Publicado: (2017)

ROCK1 Mediates Retinal Glial Cell Migration Promoted by Acrolein
por: Fukutsu, Kanae, et al.
Publicado: (2021)

Retinal Glial and Choroidal Vascular Pathology in Donors Clinically Diagnosed With Stargardt Disease
por: Edwards, Malia M., et al.
Publicado: (2020)

Nestin Regulates Müller Glia Proliferation After Retinal Injury
por: Motoyoshi, Aya, et al.
Publicado: (2023)

Epigenetic mechanisms of Müller glial reprogramming mediating retinal regeneration
por: Si, Tian-En, et al.
Publicado: (2023)

Conditional Müller Cell Ablation Leads to Retinal Iron Accumulation
por: Baumann, Bailey, et al.
Publicado: (2017)

Effectively Intervening Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells With a Combination of ROCK and TGF-β Signaling Inhibitors
por: Chen, Yi, et al.
Publicado: (2021)

The transcriptome of retinal Müller glial cells
por: Roesch, Karin, et al.
Publicado: (2008)

Retinal Degeneration Triggers the Activation of YAP/TEAD in Reactive Müller Cells
por: Hamon, Annaïg, et al.
Publicado: (2017)

Coordinated Intervention of Microglial and Müller Cells in Light-Induced Retinal Degeneration
por: Di Pierdomenico, Johnny, et al.
Publicado: (2020)

Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture
por: Wohl, Stefanie G., et al.
Publicado: (2017)

Antiviral Drug Ganciclovir Is a Potent Inhibitor of the Proliferation of Müller Glia–Derived Progenitors During Zebrafish Retinal Regeneration
por: Zhang, Shuqiang, et al.
Publicado: (2016)

Beneficial Effects of Berberine on Oxidized LDL-Induced Cytotoxicity to Human Retinal Müller Cells
por: Fu, Dongxu, et al.
Publicado: (2016)

High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy
por: Tien, Thomas, et al.
Publicado: (2017)

Blockade of Platelet-Derived Growth Factor Signaling Inhibits Choroidal Neovascularization and Subretinal Fibrosis in Mice
por: Liu, Ye, et al.
Publicado: (2020)

The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar
por: Conedera, Federica Maria, et al.
Publicado: (2021)

Rapamycin and Resveratrol Modulate the Gliotic and Pro-Angiogenic Response in Müller Glial Cells Under Hypoxia
por: Subirada, Paula V., et al.
Publicado: (2022)

K(ATP) Opener Attenuates Diabetic-Induced Müller Gliosis and Inflammation by Modulating Kir6.1 in Microglia
por: Li, Hong, et al.
Publicado: (2021)

Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Müller Cells of Diabetic Human and Rodent Retina
por: Hu, Ping, et al.
Publicado: (2017)

Specific tools for targeting and expression in Müller glial cells
por: Pellissier, Lucie P, et al.
Publicado: (2014)

Neural and Müller glial adaptation of the retina to photoreceptor degeneration
por: Leinonen, Henri O., et al.
Publicado: (2022)

Regulation and Signaling of TGF-β Autoinduction
por: Hariyanto, Narendra Ichiputra, et al.
Publicado: (2021)

MicroRNA 9 Is a Regulator of Endothelial to Mesenchymal Transition in Diabetic Retinopathy
por: Wang, Eric, et al.
Publicado: (2023)

Potential role of sirtuin 1 in Müller glial cells in mice choroidal neovascularization
por: Ishida, Tomoka, et al.
Publicado: (2017)

Single Cell RNA Sequencing Analysis of Mouse Retina Identifies a Subpopulation of Muller Glia Involved in Retinal Recovery From Injury in the FCD-LIRD Model
por: Aredo, Bogale, et al.
Publicado: (2023)

Plasmalogens Regulate Retinal Connexin 43 Expression and Müller Glial Cells Gap Junction Intercellular Communication and Migration
por: Karadayi, Rémi, et al.
Publicado: (2022)

GABA and Glutamate Uptake and Metabolism in Retinal Glial (Müller) Cells
por: Bringmann, Andreas, et al.
Publicado: (2013)

Dyslipidemia modulates Müller glial sensing and transduction of ambient information
por: Lakk, Monika, et al.
Publicado: (2018)

SIRT4 Is Highly Expressed in Retinal Müller Glial Cells
por: Wei, Wei, et al.
Publicado: (2022)

Müller glial responses compensate for degenerating photoreceptors in retinitis pigmentosa
por: Tomita, Yohei, et al.
Publicado: (2021)

Compartmentalized citrullination in Muller glial endfeet during retinal degeneration
por: Palko, Sarah I., et al.
Publicado: (2022)

Genetic and epigenetic regulators of retinal Müller glial cell reprogramming
por: Xiao, Xueqi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_frsgoe9rapc29m1sd8qha0r8up