Development of a Corneal Bioluminescence Mouse for Real-Time In Vivo Evaluation of Gene Therapies

PURPOSE: The purpose of this study was to develop and characterize a novel bioluminescence transgenic mouse model that facilitates rapid evaluation of genetic medicine delivery methods for inherited and acquired corneal diseases. METHODS: Corneal expression of the firefly luciferase transgene (luc2)...

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Detalles Bibliográficos
Autores principales: Fu, Dun Jack, Allen, Edwin H. A., Hickerson, Robyn P., Leslie Pedrioli, Deena M., McLean, W. H. Irwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774114/
https://www.ncbi.nlm.nih.gov/pubmed/33442498
http://dx.doi.org/10.1167/tvst.9.13.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774114/
https://www.ncbi.nlm.nih.gov/pubmed/33442498
http://dx.doi.org/10.1167/tvst.9.13.44

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