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Cyclopenta[b]indole Derivative Inhibits Aurora B in Primary Cells

[Image: see text] The Aurora family of kinases is closely involved in regulating cell division. Inhibition of Aurora A and B with small molecules is currently being investigated in clinical trials for the treatment of different cancers. It has also been evaluated as a treatment option against differ...

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Detalles Bibliográficos
Autores principales: Ekebergh, Andreas, Mårtensson, Jerker, Ekebergh, Christine Lingblom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774273/
https://www.ncbi.nlm.nih.gov/pubmed/33403307
http://dx.doi.org/10.1021/acsomega.0c05491