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Dimerization of Doxorubicin Causes Its Precipitation

[Image: see text] Doxorubicin (DOX) is commonly used in chemotherapy and biomedical research because of its potent anticancer activity. Although DOX is water soluble, it precipitates when interacting with buffers, such as phosphate-buffered saline, or with drugs such as 5-fluorouracil (5-FU) and hep...

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Detalles Bibliográficos
Autor principal: Yamada, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774281/
https://www.ncbi.nlm.nih.gov/pubmed/33403285
http://dx.doi.org/10.1021/acsomega.0c04925