Structural Insights into the Atomistic Mechanisms of Uric Acid Recognition and Translocation of Human Urate Anion Transporter 1

[Image: see text] Background: Human urate transporter 1 (hURAT1) is the most pivotal therapeutic target for treating hyperuricemia. However, the molecular interactions between uric acid and URAT1 are still unknown due to lack of structural details. Methods: In the present study, several methods (hom...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Ze’an, Jiang, Yu, Li, Lu, Chen, Yanyu, Li, Yongmei, Lan, Qunsheng, Wu, Ting, Lin, Cuiting, Cao, Ying, Nandakumar, Kutty Selva, Zhou, Pingzheng, Tian, Yuanxin, Pang, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774290/
https://www.ncbi.nlm.nih.gov/pubmed/33403304
http://dx.doi.org/10.1021/acsomega.0c05360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774290/
https://www.ncbi.nlm.nih.gov/pubmed/33403304
http://dx.doi.org/10.1021/acsomega.0c05360

Ejemplares similares