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Structural Insights into the Atomistic Mechanisms of Uric Acid Recognition and Translocation of Human Urate Anion Transporter 1

[Image: see text] Background: Human urate transporter 1 (hURAT1) is the most pivotal therapeutic target for treating hyperuricemia. However, the molecular interactions between uric acid and URAT1 are still unknown due to lack of structural details. Methods: In the present study, several methods (hom...

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Detalles Bibliográficos
Autores principales:	Zhao, Ze’an, Jiang, Yu, Li, Lu, Chen, Yanyu, Li, Yongmei, Lan, Qunsheng, Wu, Ting, Lin, Cuiting, Cao, Ying, Nandakumar, Kutty Selva, Zhou, Pingzheng, Tian, Yuanxin, Pang, Jianxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774290/ https://www.ncbi.nlm.nih.gov/pubmed/33403304 http://dx.doi.org/10.1021/acsomega.0c05360

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