Semi-Mechanistic Modeling of HY-021068 Based on Irreversible Inhibition of Thromboxane Synthetase

Background: HY-021068 [4-(2-(1H-imidazol-1-yl) ethoxy)-3-methoxybenzoate], developed by Hefei Industrial Pharmaceutical Institute Co., Ltd. (Anhui, China), is a potential thromboxane synthetase inhibitor under development as an anti-platelet agent for the treatment of stroke. A semi-mechanistic phar...

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Detalles Bibliográficos
Autores principales: Li, Ping, Huang, Jie, Geng, Donghao, Liu, Peihua, Chu, Zhaoxing, Zou, Jianjun, Yang, Guoping, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774308/
https://www.ncbi.nlm.nih.gov/pubmed/33390963
http://dx.doi.org/10.3389/fphar.2020.588286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774308/
https://www.ncbi.nlm.nih.gov/pubmed/33390963
http://dx.doi.org/10.3389/fphar.2020.588286

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