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CD73 alleviates GSDMD‐mediated microglia pyroptosis in spinal cord injury through PI3K/AKT/Foxo1 signaling

BACKGROUND: Neuroinflammation‐induced secondary injury is an important cause of sustained progression of spinal cord injury. Inflammatory programmed cell death pyroptosis executed by the pore‐forming protein gasdermin D (GSDMD) is an essential step of neuroinflammation. However, it is unclear whethe...

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Detalles Bibliográficos
Autores principales: Xu, Shun, Wang, Jin, Zhong, Junjie, Shao, Minghao, Jiang, Jianyuan, Song, Jian, Zhu, Wei, Zhang, Fan, Xu, Haocheng, Xu, Guangyu, Zhang, Yuxuan, Ma, Xiaosheng, Lyu, Feizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774461/
https://www.ncbi.nlm.nih.gov/pubmed/33463071
http://dx.doi.org/10.1002/ctm2.269