Cargando…
CD73 alleviates GSDMD‐mediated microglia pyroptosis in spinal cord injury through PI3K/AKT/Foxo1 signaling
BACKGROUND: Neuroinflammation‐induced secondary injury is an important cause of sustained progression of spinal cord injury. Inflammatory programmed cell death pyroptosis executed by the pore‐forming protein gasdermin D (GSDMD) is an essential step of neuroinflammation. However, it is unclear whethe...
Autores principales: | Xu, Shun, Wang, Jin, Zhong, Junjie, Shao, Minghao, Jiang, Jianyuan, Song, Jian, Zhu, Wei, Zhang, Fan, Xu, Haocheng, Xu, Guangyu, Zhang, Yuxuan, Ma, Xiaosheng, Lyu, Feizhou |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774461/ https://www.ncbi.nlm.nih.gov/pubmed/33463071 http://dx.doi.org/10.1002/ctm2.269 |
Ejemplares similares
-
TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury
por: Xu, Shun, et al.
Publicado: (2020) -
Ecto-5′-nucleotidase (CD73) attenuates inflammation after spinal cord injury by promoting macrophages/microglia M2 polarization in mice
por: Xu, Shun, et al.
Publicado: (2018) -
TLR4 aggravates microglial pyroptosis by promoting DDX3X‐mediated NLRP3 inflammasome activation via JAK2/STAT1 pathway after spinal cord injury
por: Wang, Jin, et al.
Publicado: (2022) -
Disulfiram alleviates pristane-induced lupus via inhibiting GSDMD-mediated pyroptosis
por: Zhuang, Lili, et al.
Publicado: (2022) -
Quantitative analysis of near-implant magnesium accumulation for a Si-containing coated AZ31 cage from a goat cervical spine fusion model
por: Zhang, Fan, et al.
Publicado: (2018)