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Fatal Case of Chronic Jamestown Canyon Virus Encephalitis Diagnosed by Metagenomic Sequencing in Patient Receiving Rituximab

A 56-year-old man receiving rituximab who had months of neurologic symptoms was found to have Jamestown Canyon virus in cerebrospinal fluid by clinical metagenomic sequencing. The patient died, and postmortem examination revealed extensive neuropathologic abnormalities. Deep sequencing enabled detai...

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Detalles Bibliográficos
Autores principales: Solomon, Isaac H., Ganesh, Vijay S., Yu, Guixia, Deng, Xian Ding, Wilson, Michael R., Miller, Steve, Milligan, Tracey A., Mukerji, Shibani S., Mathewson, Abigail, Linxweiler, Justin, Morse, Darlene, Ritter, Jana M., Staples, J. Erin, Hughes, Holly, Gould, Carolyn V., Sabeti, Pardis C., Chiu, Charles Y., Piantadosi, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774567/
https://www.ncbi.nlm.nih.gov/pubmed/33261720
http://dx.doi.org/10.3201/eid2701.203448