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Increase in Kelch 13 Polymorphisms in Plasmodium falciparum, Southern Rwanda

Artemisinin resistance in Plasmodium falciparum is associated with nonsynonymous mutations in the Kelch 13 (K13) propeller domain. We found that 12.1% (8/66) of clinical P. falciparum isolates from Huye district, Rwanda, exhibited K13 mutations, including R561H, a validated resistance marker. K13 mu...

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Detalles Bibliográficos
Autores principales: Bergmann, Clara, van Loon, Welmoed, Habarugira, Felix, Tacoli, Costanza, Jäger, Julia C., Savelsberg, Darius, Nshimiyimana, Fabian, Rwamugema, Elias, Mbarushimana, Djibril, Ndoli, Jules, Sendegeya, Augustin, Bayingana, Claude, Mockenhaupt, Frank P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774571/
https://www.ncbi.nlm.nih.gov/pubmed/33350925
http://dx.doi.org/10.3201/eid2701.203527