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Competition between two phosphatases fine-tunes Hedgehog signaling

Hedgehog (Hh) signaling is essential for embryonic development and adult homeostasis. How its signaling activity is fine-tuned in response to fluctuated Hh gradient is less known. Here, we identify protein phosphatase V (PpV), the catalytic subunit of protein phosphatase 6, as a homeostatic regulato...

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Detalles Bibliográficos
Autores principales: Liu, Min, Liu, Aiguo, Wang, Jie, Zhang, Yansong, Li, Yajuan, Su, Ying, Zhu, Alan Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774589/
https://www.ncbi.nlm.nih.gov/pubmed/33373452
http://dx.doi.org/10.1083/jcb.202010078