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An antibody‐drug conjugate targeting a GSTA glycosite‐signature epitope of MUC1 expressed by non‐small cell lung cancer

Antibodies targeting aberrantly glycosylated proteins are ineffective in treating cancer. Antibody‐drug conjugates have emerged as effective alternatives, facilitating tumor‐specific drug delivery. Previous studies have assessed the aberrantly glycosylated tandem repeat region of MUC1 glycoprotein a...

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Detalles Bibliográficos
Autores principales: Pan, Deng, Tang, Yubo, Tong, Jiao, Xie, Chengmei, Chen, Jiaxi, Feng, Chunchao, Hwu, Patrick, Huang, Wei, Zhou, Dapeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774737/
https://www.ncbi.nlm.nih.gov/pubmed/33084221
http://dx.doi.org/10.1002/cam4.3554