Akt1 genetic variants confer increased susceptibility to thyroid cancer

The PI3K-Akt-mTOR pathway plays a central role in the development of non-medullary thyroid carcinoma (NMTC). Although somatic mutations have been identified in these genes in NMTC patients, the role of germline variants has not been investigated. Here, we selected frequently occurring genetic varian...

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Detalles Bibliográficos
Autores principales: Crezee, Thomas, Petrulea, Mirela, Piciu, Doina, Jaeger, Martin, Smit, Jan W A, Plantinga, Theo S, Georgescu, Carmen E, Netea-Maier, Romana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774771/
https://www.ncbi.nlm.nih.gov/pubmed/33112820
http://dx.doi.org/10.1530/EC-20-0311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774771/
https://www.ncbi.nlm.nih.gov/pubmed/33112820
http://dx.doi.org/10.1530/EC-20-0311

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