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Calcium dynamics and chromatin remodelling underlie heterogeneity in prolactin transcription

Pituitary cells have been reported to show spontaneous calcium oscillations and dynamic transcription cycles. To study both processes in the same living cell in real time, we used rat pituitary GH3 cells stably expressing human prolactin-luciferase or prolactin-EGFP reporter gene constructs loaded w...

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Detalles Bibliográficos
Autores principales: Harper, Claire V, McNamara, Anne V, Spiller, David G, Charnock, Jayne C, White, Michael R H, Davis, Julian R E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774774/
https://www.ncbi.nlm.nih.gov/pubmed/33112804
http://dx.doi.org/10.1530/JME-20-0223