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Widespread Glial Activation in Primary Progressive Multiple Sclerosis Revealed by (18)F-PBR06 PET: A Clinically Feasible, Individualized Approach

A 64-year-old man with primary progressive multiple sclerosis (Expanded Disability Status Scale 3.5) underwent PET using (18)F-PBR06, a second-generation 18-kDa translocator protein ligand targeting activated brain microglia and astrocytes. Voxel-by-voxel statistical comparison of patient’s PET imag...

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Detalles Bibliográficos
Autores principales: Singhal, Tarun, Rissanen, Eero, Ficke, John, Cicero, Steven, Carter, Kelsey, Weiner, Howard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774808/
https://www.ncbi.nlm.nih.gov/pubmed/33208611
http://dx.doi.org/10.1097/RLU.0000000000003398