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Widespread Glial Activation in Primary Progressive Multiple Sclerosis Revealed by (18)F-PBR06 PET: A Clinically Feasible, Individualized Approach
A 64-year-old man with primary progressive multiple sclerosis (Expanded Disability Status Scale 3.5) underwent PET using (18)F-PBR06, a second-generation 18-kDa translocator protein ligand targeting activated brain microglia and astrocytes. Voxel-by-voxel statistical comparison of patient’s PET imag...
Autores principales: | Singhal, Tarun, Rissanen, Eero, Ficke, John, Cicero, Steven, Carter, Kelsey, Weiner, Howard L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774808/ https://www.ncbi.nlm.nih.gov/pubmed/33208611 http://dx.doi.org/10.1097/RLU.0000000000003398 |
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