Cargando…

Harmine enhances the activity of the HIV-1 latency-reversing agents ingenol A and SAHA

Infection with human immunodeficiency virus 1 (HIV-1) remains incurable because long-lived, latently-infected cells persist during prolonged antiretroviral therapy. Attempts to pharmacologically reactivate and purge the latent reservoir with latency reactivating agents (LRAs) such as protein kinase...

Descripción completa

Detalles Bibliográficos
Autores principales: Taylor, Jared P., Armitage, Lucas H., Aldridge, Daniel L., Cash, Melanie N., Wallet, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774897/
https://www.ncbi.nlm.nih.gov/pubmed/33234703
http://dx.doi.org/10.1242/bio.052969