Hypoxia-inducible factor 1 alpha limits dendritic cell stimulation of CD8 T cell immunity

Dendritic cells are sentinels of the immune system and represent a key cell in the activation of the adaptive immune response. Hypoxia-inducible factor 1 alpha (HIF-1α)–a crucial oxygen sensor stabilized during hypoxic conditions–has been shown to have both activating and inhibitory effects in immun...

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Detalles Bibliográficos
Autores principales: Tran, Charles W., Gold, Matthew J., Garcia-Batres, Carlos, Tai, Kelly, Elford, Alisha R., Himmel, Megan E., Elia, Andrew J., Ohashi, Pamela S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775062/
https://www.ncbi.nlm.nih.gov/pubmed/33382742
http://dx.doi.org/10.1371/journal.pone.0244366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775062/
https://www.ncbi.nlm.nih.gov/pubmed/33382742
http://dx.doi.org/10.1371/journal.pone.0244366

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