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SlitC-PlexinA1 mediates iterative inhibition for orderly passage of spinal commissural axons through the floor plate

Spinal commissural axon navigation across the midline in the floor plate requires repulsive forces from local Slit repellents. The long-held view is that Slits push growth cones forward and prevent them from turning back once they became sensitized to these cues after midline crossing. We analyzed w...

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Detalles Bibliográficos
Autores principales: Ducuing, Hugo, Gardette, Thibault, Pignata, Aurora, Kindbeiter, Karine, Bozon, Muriel, Thoumine, Olivier, Delloye-Bourgeois, Céline, Tauszig-Delamasure, Servane, Castellani, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775108/
https://www.ncbi.nlm.nih.gov/pubmed/33345773
http://dx.doi.org/10.7554/eLife.63205