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NLRC3 Delays the Progression of AD in APP/PS1 Mice via Inhibiting PI3K Activation

NLRC3 inhibits inflammatory responses. Neuroinflammation induces and accelerates the onset of Alzheimer's disease (AD). This study is aimed at investigating whether NLRC3 plays a role in neuroinflammation, Aβ accumulation, and neuroprotection in AD mice. 12-month-old APP/PS1 transgenic and C57...

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Detalles Bibliográficos
Autores principales: Zha, Lihuang, Yu, Zaixin, Fang, Jian, Zhou, Li, Guo, Wen, Zhou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775163/
https://www.ncbi.nlm.nih.gov/pubmed/33425209
http://dx.doi.org/10.1155/2020/5328031