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Azelaic Acid Exerts Antileukemia Effects against Acute Myeloid Leukemia by Regulating the Prdxs/ROS Signaling Pathway

Acute myeloid leukemia (AML) is a hematological malignancy with a poor prognosis attributed to elevated reactive oxygen species (ROS) levels. Thus, agents that inhibit ROS generation in AML should be exploited. Azelaic acid (AZA), a small molecular compound, can scavenge ROS and other free radicals,...

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Detalles Bibliográficos
Autores principales: Zhang, Dongdong, Luo, Ziyi, Jin, Yanxia, Chen, Yanling, Yang, Tian, Yang, Qian, Wu, Balu, Shang, Yufeng, Liu, Xiaoyan, Wei, Yongchang, Zhou, Fuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775164/
https://www.ncbi.nlm.nih.gov/pubmed/33425206
http://dx.doi.org/10.1155/2020/1295984