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Rapid Evolution of HERC6 and Duplication of a Chimeric HERC5/6 Gene in Rodents and Bats Suggest an Overlooked Role of HERCs in Mammalian Immunity

Studying the evolutionary diversification of mammalian antiviral defenses is of main importance to better understand our innate immune repertoire. The small HERC proteins are part of a multigene family, including HERC5 and HERC6, which have probably diversified through complex evolutionary history i...

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Detalles Bibliográficos
Autores principales: Jacquet, Stéphanie, Pontier, Dominique, Etienne, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775381/
https://www.ncbi.nlm.nih.gov/pubmed/33391270
http://dx.doi.org/10.3389/fimmu.2020.605270